Development of a Nuclear Morphometric Signature for Prostate Cancer Risk in Negative Biopsies
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چکیده
منابع مشابه
Development of a Nuclear Morphometric Signature for Prostate Cancer Risk in Negative Biopsies
BACKGROUND Our objective was to develop and validate a multi-feature nuclear score based on image analysis of direct DNA staining, and to test its association with field effects and subsequent detection of prostate cancer (PCa) in benign biopsies. METHODS Tissue sections from 39 prostatectomies were Feulgen-stained and digitally scanned (400×), providing maps of DNA content per pixel. PCa and...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2013
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0069457